Tyrosine kinase-IN-1
CAS No. 705946-27-6
Tyrosine kinase-IN-1 ( —— )
产品货号. M20206 CAS No. 705946-27-6
Tyrosine kinase-IN-1 is a multi-targeted tyrosine kinase inhibitor(KDR Flt-1 FGFR1 and PDGFRα with IC50s of 4nM 20nM 4nM 2 nM respectively).
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
规格 | 价格/人民币 | 库存 | 数量 |
5MG | ¥583 | 有现货 |
|
10MG | ¥988 | 有现货 |
|
25MG | ¥2001 | 有现货 |
|
50MG | ¥2989 | 有现货 |
|
100MG | ¥4447 | 有现货 |
|
200MG | 获取报价 | 有现货 |
|
500MG | 获取报价 | 有现货 |
|
1G | 获取报价 | 有现货 |
|
生物学信息
-
产品名称Tyrosine kinase-IN-1
-
注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
-
产品简述Tyrosine kinase-IN-1 is a multi-targeted tyrosine kinase inhibitor(KDR Flt-1 FGFR1 and PDGFRα with IC50s of 4nM 20nM 4nM 2 nM respectively).
-
产品描述Tyrosine kinase-IN-1 is a multi-targeted tyrosine kinase inhibitor(KDR Flt-1 FGFR1 and PDGFRα with IC50s of 4nM 20nM 4nM 2 nM respectively)
-
同义词——
-
通路Angiogenesis
-
靶点VEGFR
-
受体KDR;Flt-1;FGFR1;PDGFRα;PDGFRα
-
研究领域——
-
适应症——
化学信息
-
CAS Number705946-27-6
-
分子量445.54
-
分子式C26H28FN5O
-
纯度>98% (HPLC)
-
溶解度DMSO:62.5 mg/mL (160.47 mM)
-
SMILESCCN1CCC(CC1)Nc1ccc2NC(=O)\C(=C(/c3ncc(C)[nH]3)c3cccc(F)c3)c2c1
-
化学全称(Z)-5-((1-ethylpiperidin-4-yl)amino)-3-((3-fluorophenyl)(5-methyl-1H-imidazol-2-yl)methylene)indolin-2-one
运输与储存
-
储存条件(-20℃)
-
运输条件With Ice Pack
-
稳定性≥ 2 years
参考文献
1.Moon K et al. The design synthesis and biological evaluation of potent receptor tyrosine kinase inhibitors. Bioorganic & Medicinal Chemistry Letters 22 (2012) 4979–4985
产品手册
关联产品
-
Brivanib
A dual inhibitor of VEGFR2 and FGFR1 with IC50 of 25 nM and 148 nM respectively.
-
Asimadoline hydrochl...
Asimadoline HCl is a κ-opioid receptor agonist potentially for the treatment of pruritus. Asimadoline has also been shown to be used in the treatment of irritable bowel syndrome.
-
BFH-772
A potent, selective and orally active VEGFR2 tyrosine kinase inhibitor with IC50 of 3 nM.