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Tyrosine kinase-IN-1

CAS No. 705946-27-6

Tyrosine kinase-IN-1 ( —— )

产品货号. M20206 CAS No. 705946-27-6

Tyrosine kinase-IN-1 is a multi-targeted tyrosine kinase inhibitor(KDR Flt-1 FGFR1 and PDGFRα with IC50s of 4nM 20nM 4nM 2 nM respectively).

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ¥583 有现货
10MG ¥988 有现货
25MG ¥2001 有现货
50MG ¥2989 有现货
100MG ¥4447 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    Tyrosine kinase-IN-1
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    Tyrosine kinase-IN-1 is a multi-targeted tyrosine kinase inhibitor(KDR Flt-1 FGFR1 and PDGFRα with IC50s of 4nM 20nM 4nM 2 nM respectively).
  • 产品描述
    Tyrosine kinase-IN-1 is a multi-targeted tyrosine kinase inhibitor(KDR Flt-1 FGFR1 and PDGFRα with IC50s of 4nM 20nM 4nM 2 nM respectively)
  • 同义词
    ——
  • 通路
    Angiogenesis
  • 靶点
    VEGFR
  • 受体
    KDR;Flt-1;FGFR1;PDGFRα;PDGFRα
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    705946-27-6
  • 分子量
    445.54
  • 分子式
    C26H28FN5O
  • 纯度
    >98% (HPLC)
  • 溶解度
    DMSO:62.5 mg/mL (160.47 mM)
  • SMILES
    CCN1CCC(CC1)Nc1ccc2NC(=O)\C(=C(/c3ncc(C)[nH]3)c3cccc(F)c3)c2c1
  • 化学全称
    (Z)-5-((1-ethylpiperidin-4-yl)amino)-3-((3-fluorophenyl)(5-methyl-1H-imidazol-2-yl)methylene)indolin-2-one

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Moon K et al. The design synthesis and biological evaluation of potent receptor tyrosine kinase inhibitors. Bioorganic & Medicinal Chemistry Letters 22 (2012) 4979–4985
产品手册
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